Naslov (eng)

COMPARATIVE CHEMICAL STUDY OF THREE JUNIPERUS SPECIES

Autor

Tadić, Vanja
Žugić, Ana
Bojović, Dragica
Šoškić, Miomir
Nešić, Ivana

Opis (eng)

Plant-derived products and their compounds have been used in traditional medicine since early times. Recent works report promising potential regarding the use of plants in the treatment and/or prevention of several hardto- cure diseases, such as atherosclerosis, cancer, cardiovascular diseases, diabetes, and neurological disorders, among others. The genus Juniperus has been recognized as the source of valuable active compounds. This genus includes roughly 68 species and 36 varieties and belongs to the Cupressaceae family. This work gave insight into differences in chemical composition and antioxidative properties of three Juniperus sp., namely J. communis L. (common juniper), J. oxycedrus L. (prickly juniper) and J. sibirica L. (Siberian juniper). Common juniper (J. communis L.), based on the information provided by EMA monograph and PDR, is traditionally used to treat renal suppression, acute and chronic cystitis, bladder catarrh, albuminuria, leucorrhea, and amenorrhea. These uses are mainly attributed to its bioactive compounds belonging to different secondary metabolite groups, such as polyphenols, terpenoids, organic acids, flavonoids, tannins. While the data on common juniper are abundant, the investigations considering the prickly and Siberian juniper are scarce. The folium and ripe pseudofructus from all three species were collected from a locality in Montenegro (Plav, the mountain Čakor) in August 2019. The extraction method was maceration, performed using 70% EtOH, the plant material was ground until the particle size was 0.7 mm, while the drug:extract ratio was kept to be 1:5. To determine total phenolics, Folin–Ciocalteu (FC) spectrophotometric method was applied, while total procyanidins and tannins were estimated by following the procedure described in 10th European Pharmacopoeia. The antioxidant capacity of extracts was assessed by the DPPH and FRAP assays. The obtained results (Table 1) pointed out the differences between the investigated species. While the TP content was similar in J. communis and J. oxycedrus, J. sibirica although less abundant in tannin and polyphenolic content, exhibited significant antioxidant properties, comparable to control (BHT).

Jezik

engleski

Datum

2025

Licenca

© All rights reserved

Predmet

Juniperus sp., maceration, chemical and antioxidant properties.

Deo kolekcije (1)

o:2594

Radovi nastavnika i saradnika Instituta za proučavanje lekovitog bilja "Dr Josif Pančić"