Naslov (eng)

The presence of virulence-related genes among Listeria Monocytogenes strains and their correlation with pathogenic potential

Autor

Lakićević, Brankica
Velebit, Branko
Janković, Vesna V.
Mitrović, Radmila
Milojević, Lazar
Mišić, Dunja
Mrdović, Boris

Publisher

Opis (eng)

Listeria monocytogenes remains a significant public health concern due to its high mortality rate in susceptible individuals. Contaminated food, particularly ready-to-eat products, are the primary route of transmission to humans. Previous studies have shown that L. monocytogenes exhibits heterogeneous virulence, with strains ranging from hypervirulent to hypovirulent. L. monocytogenes has been found to have pathogenicity islands and other virulence factors scat- tered across the bacterial genome (e.g. inlAB locus). Further, the inlA-inlB locus and LIPI-1 are conserved in almost all L. monocytogenes isolates, emphasizing their important role for pathogenicity. Literature data showed that using genetic virulence profiles to predict virulence potential offers useful information for risk assessment in the food sector, although it also has drawbacks. Also, the use of whole-genome sequencing as the gold standard approach, enhanc- es quantitative microbiological risk assessment and improve listeriosis control.

Jezik

engleski

Datum

2025-12-01

Licenca

Ovo delo je licencirano pod uslovima licence
Creative Commons CC BY 4.0 - Creative Commons Autorstvo 4.0 International License.

http://creativecommons.org/licenses/by/4.0/legalcode

Predmet

Listeria monocytogenes, Virulence factors, Pathogenicity islands, Listeriosis

Deo kolekcije (1)

o:32

Institut za higijenu i tehnologiju mesa