Naslov (eng)

Blue maize as source of anthocyanins with diverse pharmacological activities: Microencapsulation and fate during accelerated aging and in vitro gastrointestinal digestion

Autor

Žilić, Slađana
Nikolić, Valentina
Ćujić Nikolić, Nada
Simić, Marijana
Šavikin, Katarina
Živković, Jelena
Sarić, Beka
Milovanović, Danka

Publisher

Opis (eng)

Among other plant species, cereal grains can also be a source of anthocyanins (ACNs). Whole-grain flour of colored maize has primarily found application in the production of bakery and confectionery foodstuffs. However, application of ACNs originating from maize grains in pharmacy requires their isolation and represent a certain challenge. The aim of the research was to develop microencapsulation systems of ACNs from waste product of blue maize processing using maltodextrin (MD) and hydroxypropyl-β-cyclodextrin (HPCD). Liquid blue maize extract was spray dried with and without adding carrier agents: MD (30%), HPCD (30%) and combination of both carriers (15% MD and 15% HPCD). The obtained samples were analyzed for the content of ACNs before and after accelerated aging, as well as for the fate of ACNs in the digestive system. Total ACNs content in the spray dried maize extract (SME) was 12846 mg CGE/kg, with acylated Cy-3-(6'-Mal-Glu) than Cy-3-Glu as dominant. Microencapsulates had a lower content of total anthocyanins by 16, 14 and 26% compared to SME, respectively. Cavity and hollow molecular shape of the CDs make them ideal carrier to decrease phenolic compounds loss. So, after aging, the content of total ACNs detected by HPLC was 11% lower in microencapsulates with MD, compared to that before aging, while in miroencapsulates with HPCD the difference was not statistically significant. Due to the action of digestive enzymes, in the first and last stage of digestion of SME and microencapsulates with MD, HPCD and MD+HPCD, the content of ACNs in the fluids was 59, 66, 67 and 64% i.e. 49, 42, 57 and 56%, respectively, of their initial value. Waste product of blue maize processing in form of microencapsulates can contribute significantly to the daily intake of ACNs, especially acylated forms whose daily intake has been estimated at 23% compared to 77% of non-acylated ones.

Jezik

engleski

Datum

2025

Licenca

© All rights reserved

Predmet

blue maize; processing waste; anthocyanins; microencapsulation; fate during aging and digestion

Deo kolekcije (1)

o:2594

Radovi nastavnika i saradnika Instituta za proučavanje lekovitog bilja "Dr Josif Pančić"