FORMULATION OF HONEY-BASED SUPPLEMENT ENRICHED WITH MICROENCAPSULATED CHOKEBERRY POMACE EX
The aim of the study was to obtain an added-value supplement based on honey and microencapsulated chokeberry pomace extract. The fruits were pressed to obtain juice pomace. The influence of different temperatures and length of drying of the pomace on the content of bioactive ingredients was examined and the following conditions were chosen as optimal: a temperature of 45°C; drying time of 36 hours. After extraction optimization the following parameters were selected as optimal: extraction time of 90 minutes, 50% ethanol and a ratio of drug to solvent of 1:10. The quantification of individual anthocyanins (cyanidin galactoside, cyanidin glucoside, cyanidin arabinoside and cyanidin xyloside) was performed using HPLC where cyanidin galactoside was the most abundant (6.82±0.06 mg/g). Carriers based on hydrogels or waxes with or without addition of inulin were tested using by electrostatic extrusion encapsulation technique. Also, various process parameters that influenced the microencapsulation process were analyzed. A medium-viscosity alginate with 5% inulin was selected as carrier. Encapsulation efficiency, cyanidin galactoside release from microparticles, particle size, FTIR and SEM analysis were done. Two types of particles were prepared, i.e. non-dried and dried particles. The lyophilization conditions were optimized for drying of microparticles. During formulation, three types of honey were tested: acacia, meadow and linden. Formulations were made with 3%, 5%, 7%, 10% and 20% of microparticles in honey, with and without heating at 2 temperatures (35 and 450C). Final formulation was prepared with acacia honey, 10% of undried microparticles with heating of honey on a temperature of 35°C.
engleski
2025
© All rights reserved
|
o:2594 | Radovi nastavnika i saradnika Instituta za proučavanje lekovitog bilja "Dr Josif Pančić" |