Naslov (eng)

EFFECTS OF CHOKEBERRY AND TART CHERRY BASED DIETARY SUPPLEMENTS IN DYSLIPIDEMIC INDIVIDUALS

Autor

Bigović, Dubravka
Šavikin, Katarina
Krgović, Nemanja
Živković, Jelena

Opis (eng)

The prevalence of obesity has increased dramatically over the last several decades. It is estimated the United States approximately 40% of women and 35% of men are obese (BMI >30 kg/m2). It is of great concern is that the prevalence of obesity has also markedly increased in children. Obesity is associated with alterations in lipid metabolism, insulin resistance and metabolic syndrome, particularly when the excess adipose tissue is located in an intra-abdominal location or in the upper chest. Moreover, obesity is a great risk factor for the development of cardiovascular disease. Epidemiological studies indicated that high intake of dietary polyphenols is connected with lower risk for development of chronic diseases such as cardiovascular, diabetes, obesity, neurodegenerative. That is why polyphenols are nowadays common ingredients in lot of dietary supplements and functional foods. Polyphenols are plant secondary metabolites widely distributed in medicinal plants, red wine, many fruits and vegetables, and their derived products. According to some researches, there is 200−300 mg of dietary polyphenols in every 100 g of fresh fruits or vegetables, and the total dietary intake of polyphenols in adults is from 700 to 1700 mg/day. Various bioactivities are connected with polyphenols such as antioxidant, antimicrobial, anti-inflammatory, antineurodegenerative, anticancer, antidiabetic, antiaging etc. Previous studies showed that consumption of Aronia melanocarpa extract is correlated with a positive effect on body weight, total cholesterol, low and high-density lipoproteins. The aim of our study was to evaluate the effect of combined oral consumption of two dietary supplements based on chokeberry and tart cherry juices over a period of 90 days on cholesterol, LDL, HDL, triglycerides, thickness of subcutaneous fatty tissue in different areas and safety in 46 participants with dyslipidemia. At the level of individual respondents 11 respondents (24%) had a significant improvement in cholesterol, HDL and LDL, 10 respondents (22%) had an improvement in cholesterol and LDL while there was an improvement in triglycerides in 19 subjects (41%). Although a slight decrease in cholesterol, HDL, LDL, and triglyceride levels was observed at the group level, it was not statistically significant. On the other hand, statistically significant improvement (decrease) was recorded in the thickness of subcutaneous fatty tissue in different areas i.e. in the middle of the front abdominal wall (right and left) and in the middle of the front side of the thigh (right and left). Moreover, statistically significant improvement in BMI (body mass index) was recorded from 36.53±10.72 to 30.33±6.70 (p-value 0.0001). The levels of creatinine, urea, ALT and AST values which remained within normal limits, indicated that dietary supplements did not have negative effects on the liver and kidneys during the study.

Jezik

engleski

Datum

2025

Licenca

© All rights reserved

Predmet

chokeberry, tart cherry, juices, dyslipidemia, obesity

Deo kolekcije (1)

o:2594

Radovi nastavnika i saradnika Instituta za proučavanje lekovitog bilja "Dr Josif Pančić"